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Hirofumi Yasue Selected Research

Spasm (Spasms)

1/2019Association of East Asian Variant Aldehyde Dehydrogenase 2 Genotype (ALDH2*2*) with Coronary Spasm and Acute Myocardial Infarction.
1/2016Variant Aldehyde Dehydrogenase 2 (ALDH2*2) Is a Risk Factor for Coronary Spasm and ST-Segment Elevation Myocardial Infarction.
3/2015High incidence of coronary spasm after percutaneous coronary interventions: comparison between new generation drug-eluting stent and bare-metal stent.
12/2014Pioglitazone, a peroxisome proliferator-activated receptor γ activator, suppresses coronary spasm.
1/2014Differences and interactions between risk factors for coronary spasm and atherosclerosis--smoking, aging, inflammation, and blood pressure.
5/2012High incidence of provoked coronary spasm in the presence of a stent after myocardial infarction: therapeutic and prognostic implications.
5/2010Nitrate tolerance as a possible cause of multidrug-resistant coronary artery spasm.
4/2009Coronary spasm preferentially occurs at branch points: an angiographic comparison with atherosclerotic plaque.
5/2008Effects of a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, fluvastatin, on coronary spasm after withdrawal of calcium-channel blockers.
2/2008Coronary artery spasm--clinical features, diagnosis, pathogenesis, and treatment.
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Hirofumi Yasue Research Topics

Disease

18Spasm (Spasms)
01/2019 - 01/2002
8Heart Failure
01/2022 - 05/2002
7Hypertension (High Blood Pressure)
11/2016 - 05/2002
6Muscle Spasticity (Spastic)
01/2020 - 09/2003
6Left Ventricular Dysfunction
06/2017 - 05/2002
5Flushing
01/2019 - 01/2013
4Diabetes Mellitus
10/2018 - 01/2007
4Hypokalemia
11/2016 - 01/2007
4Inflammation (Inflammations)
12/2014 - 01/2006
4Insulin Resistance
11/2013 - 07/2003
3Coronary Artery Disease (Coronary Atherosclerosis)
01/2020 - 09/2003
3Myocardial Infarction
01/2019 - 09/2004
3Hypertrophy
10/2018 - 03/2006
3Chest Pain (Chest Pains)
07/2007 - 11/2003
3Cardiovascular Diseases (Cardiovascular Disease)
09/2004 - 08/2002
2ST Elevation Myocardial Infarction
02/2022 - 01/2016
2Pathologic Constriction (Stenosis)
12/2016 - 02/2004
2Coronary Vasospasm (Coronary Artery Vasospasm)
05/2010 - 01/2002
2Alkalosis
01/2010 - 01/2007
2Coronary Stenosis (Coronary Artery Stenosis)
05/2008 - 11/2003
2Cardiomegaly (Heart Hypertrophy)
03/2006 - 02/2003
2Essential Hypertension
02/2005 - 05/2002
2Hypercholesterolemia
07/2003 - 04/2002
1Ischemia
02/2022
1Reperfusion Injury
02/2022
1Thrombosis (Thrombus)
01/2019
1Atrial Fibrillation
10/2018
1Polyuria
11/2016
1Posterior Leukoencephalopathy Syndrome
11/2016
1Malignant Hypertension
11/2016
1Atherosclerosis
01/2014
1Metabolic Syndrome (Dysmetabolic Syndrome X)
10/2013
1Obesity
10/2013
1Neoplasms (Cancer)
06/2013
1Hyperaldosteronism (Conn Syndrome)
06/2013
1Ectopic ACTH Syndrome
01/2010
1Arteriosclerosis
04/2009
1Sudden Death
02/2008
1Cardiac Arrhythmias (Arrythmia)
02/2008
1Ventricular Tachycardia
02/2008
1Atrioventricular Block
02/2008
1Hypertriglyceridemia
10/2007
1Hypoglycemia (Reactive Hypoglycemia)
10/2007
1Hypoxia (Hypoxemia)
01/2007

Drug/Important Bio-Agent (IBA)

10Brain Natriuretic Peptide (Natrecor)FDA Link
01/2022 - 05/2002
10Acetylcholine (Acetylcholine Chloride)FDA Link
01/2020 - 07/2002
8Aldehyde DehydrogenaseIBA
02/2022 - 01/2013
7AldosteroneIBA
10/2013 - 05/2002
5NitratesIBA
01/2020 - 09/2003
5HDL CholesterolIBA
12/2016 - 01/2013
4AldehydesIBA
02/2022 - 05/2015
4Uric Acid (Urate)IBA
12/2016 - 10/2007
4C-Reactive ProteinIBA
01/2014 - 07/2007
4Natriuretic PeptidesIBA
07/2007 - 05/2002
3LipidsIBA
01/2014 - 01/2006
3Calcium Channel Blockers (Blockers, Calcium Channel)IBA
05/2012 - 08/2007
3Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA
11/2007 - 11/2003
2Mitochondrial Aldehyde DehydrogenaseIBA
02/2022 - 01/2020
2Nitroglycerin (Dynamite)FDA LinkGeneric
01/2020 - 07/2002
2Biomarkers (Surrogate Marker)IBA
10/2018 - 11/2013
2Antihypertensive Agents (Antihypertensives)IBA
11/2016 - 01/2010
2Pioglitazone (Actos)FDA Link
12/2014 - 06/2013
2Peroxisome Proliferator-Activated Receptors (PPAR)IBA
12/2014 - 06/2013
2Glucose (Dextrose)FDA LinkGeneric
01/2014 - 11/2013
2Pharmaceutical PreparationsIBA
06/2013 - 05/2008
2Nonesterified Fatty Acids (NEFA)IBA
01/2013 - 10/2007
2Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
05/2010 - 05/2008
2Angiotensin Receptor AntagonistsIBA
01/2010 - 09/2003
2Adrenocorticotropic Hormone (ACTH)FDA Link
01/2010 - 02/2005
2Spironolactone (Aldactone)FDA LinkGeneric
01/2010 - 01/2007
2Hydrocortisone (Cortisol)FDA LinkGeneric
01/2010 - 02/2005
2AntioxidantsIBA
07/2007 - 01/2007
2ThioredoxinsIBA
07/2007 - 02/2004
2Dehydroepiandrosterone (DHEA)IBA
09/2004 - 07/2003
2Cytochrome P-450 CYP11B2 (CYP11B2)IBA
02/2003 - 08/2002
1Hemoglobins (Hemoglobin)IBA
10/2018
1CreatineIBA
01/2016
1MetalsIBA
03/2015
1PPAR gammaIBA
06/2013
1Nifedipine (Adalat)FDA LinkGeneric
06/2013
1PPAR-gamma AgonistsIBA
06/2013
1Oxygen (Dioxygen)IBA
05/2013
1Interleukin-6 (Interleukin 6)IBA
05/2013
1Ethanol (Ethyl Alcohol)IBA
01/2013
1Sodium Chloride Symporter Inhibitors (Diuretics, Thiazide)IBA
01/2010
1Oxidoreductases (Dehydrogenase)IBA
05/2008
1FluvastatinFDA Link
05/2008
1Coenzyme A (CoA)IBA
05/2008
1Nitric Oxide (Nitrogen Monoxide)FDA Link
02/2008
1Nitric Oxide Synthase (NO Synthase)IBA
02/2008
1Genetic Markers (Genetic Marker)IBA
11/2007
1AdiponectinIBA
10/2007
1human NPPA protein (carperitide)IBA
07/2007
1Atrial Natriuretic Factor (ANF)IBA
07/2007
1Furosemide (Lasix)FDA LinkGeneric
07/2007
1PotassiumIBA
01/2007

Therapy/Procedure

5Therapeutics
12/2014 - 09/2003
3Percutaneous Coronary Intervention
02/2022 - 03/2015
2Stents
03/2015 - 05/2012
1Drug-Eluting Stents
03/2015